Crystallization and preliminary crystallographic analysis of the DNA gyrase B protein from B-stearothermophilus

DNA gyrase B (GyrB) from B. stearothermophilus has been crystallized in the presence of the non-hydrolyzable ATP analogue, 5'-adenylpl-beta-gamma-imidodiphosphate (ADPNP), by the dialysis method. A complete native data set to 3.7 Angstrom has been collected from crystals which belonged to the cubic space group I23 with unit-cell dimension a = 250.6 Angstrom. Self-rotation function analysis indicates the position of a molecular twofold axis. Low-resolution data sets of a thimerosal and a selenomethionine derivative have also been analysed. The heavy-atom positions are consistent with one dimer in the asymmetric unit

A Report on the Preliminary design of Composite Cocured LCA Fin

A report on the preliminary design of composite cocured LCA fin is presented. A six spar structural configuration involving laminated carbon composite construction is employed in the design of torsion box. The design studies are carried out using a strength of materials based analysis. Three critical loading cases have been considered in the investigation. Results for various cases studied are presented and discussed

Induction of smectic C phase in binary mixtures of compounds with cyano end groups

We have studied binary mixtures of 4-cyanophenyl-3'-methyl-4'(4"-n-dodecylbenzoyloxy)benzoate (12 CPMBB) and 4-n-dodecylphenyl-3'-methyl-4'(4"-cyanobenzoy1oxy)benzoate (12 PMCBB). The former compound exhibits nematic, smectic A and reentrant nematic phases and the latter one nematic and smectic A phases with a possible AdA2, transition. Over a fairly wide composition range, the mixtures exhibit an induced smectic C phase on cooling the sample from the A phase. The phase diagram, and the temperature variations of the layer spacings for some specific compositions are reported. The possible origin of the C phase is also discussed

Emergency Intraperitoneal Onlay Mesh Repair of Incarcerated Spigelian Hernia

This report suggests that Spigelian hernia in an emergency setting may be easily and quickly repaired with an intraperitoneal onlay method using composite mesh

Benefication, sintering and processing of raw materials for the iron and steel industry

Beneficiation of iron ores relates not only to enrichment of the metal content but also to improvements in physical characteristics of the ore charged into the blast-furnace. The latter is achieved by crushing, sizing and agglo-meration of resultant fines etc. It is universally reco-ginzed that preparation of sized iron-ore burden and use of fluxed sinter in iron production can achieve (i) redu-ction in coke rate by reducing the metallurgical load on the blast-furnace by better utilization of available heat and (ii) increased productivity

Enhanced smectic a mesophase in mixtures of two terminally polar compounds

An enhanced smectic A phase has been observed in mixtures of two terminally polar compounds, viz, 5-(4-n butylphenyl)-2-(4-cyanophenyl)-pyrimidine (4 PCPP) and n-dodecyl-4-(4'-nitrobenzoyloxy) benzoate (12 NBOB). The former is a nematogen and the latter non-mesomorphic with a hidden smectic A-isotropic transition. The smectic A-nematic transition boundary shows a parabolic shape, but with an unusually large tilt angle between the axis of the parabola and the composition axis. Mixtures in some composition range exhibit the reentrant nematic phase. Xray diffraction studies indicate that the smectic phase is of the Ad type. Low frequency dielectric constants and dispersion measurements of εVerbar; are also reported

Delayed Duodenal Hematoma and Pancreatitis from a Seatbelt Injury

Traumatic duodenal hematoma is a rare condition that is encountered in the paediatric age group following blunt abdominal trauma. It poses both a diagnostic and therapeutic challenge. The main concern is increased morbidity secondary to delayed diagnosis and associated occult injuries to the adjacent structures. Most of these hematomas resolve spontaneously with conservative management, and the prognosis is good. We present a case of a 15-year-old boy who had a delayed presentation of duodenal hematoma and acute pancreatitis, which was treated conservatively with complete resolution

Sintering of Iron Ore Fines, and Raw Materials for Bhilai Steel Plant

A detailed study has been made at the National Metall-urgical Laboratory on the sintering charactersitics of the iron-ores of Rajharapahar. Madhya Pradesh, and other raw materials likely to be used in the Bhilai steel plant. The effects of variables such as coke and moisture contents in sinter mix, basicity and raw material proportions, on the sintering time and their effects on the quality of sinter produced, have been studied with a sintering plant desig-ned and fabricated at the Laboratory. Optimum conditions for producing the best sinter have been determined. Results of the tests on the Bhilai sample show that coke has a pronounced effect on sinter properties whereas moisture content directly affects permeability and sint-ering rate. 6.1% by weight of coke was found to be the optimum quantity for producing a good sinter. The optimum water content in the charge for producing the most per-meable bed was 7%. The basicity for producing a good self-fluxing sinter in the shortest time was 0.

Microrheology of non mulberry silk varieties by optical tweezer and video microscopy based techniqueas

We have carried out a comparative study of the microrheol. properties of silk fibroin solns. formed from a variety of silks indigenous to the Indian subcontinent. We present the measured viscoelastic moduli of Tasar silk fibroin soln. using both a single and dual optical tweezer at 0.16​% and 0.25​% (w​/v)​. The bandwidth of the measurements carried out using optical tweezers is extended down to the lower frequency regime by a video microscopy measurement. Further, we have measured the viscoelastic moduli of Eri and Muga varieties of silk fibroin solns. at a higher concn. (1.00​% w​/v) limiting the tool of measurement to video microscopy, as the reduced optical transparencies of these solns. at higher concn. preclude an optical tweezer based investigation. The choice of a higher concn. of fibroin soln. of the latter silk varieties is so as to enable a comparison of the shear moduli obtained from optical methods with their corresponding fiber stiffness obtained from wide angle X-​ray scattering data. We report a correlation between the microstructure and microrheol. parameters of these silk varieties for the concn. of fibroin solns. studied